Chronic heart failure (CHF)serves as a hospitalization’s primary cause for individuals beyond age 65, thereby representing burdens – such as economic and clinical. In addition, about half of hospital re-admissions are related to co-morbidities, polypharmacy, and disabilities associated with CHF (Tahhan et al., 2018). Age: Coinciding with age advancement resides the risk of heart, the primary reason for hospitalization among individuals 65 years and beyond (Tahhan et al., 2018). Gender: Males present a higher inclination towards heart failure than their female counterparts. In contrast, females present themselves with a higher disposition towards developing diastolic heart failure (heart muscle fails to enter a relaxed state) (Tahhan et al., 2018). Demographics: Heart disease trends indicate an increased likelihood of possessing a causal relationship with differences from either race or geography, dealing with treatment concerning heart disease prevention. Case in point, researchers had uncovered that within the Deep aspects of the South, traits such as the absence of physical activity, heightened blood pressure, as well as obesity was deemed conventional (Tahhan et al., 2018). Ethnicity: African-Americans are presented at a higher likelihood than their white counterparts of heart failure development prior to age 50 and pass away (Tahhan et al., 2018). Genetics and Familial history: Individuals who are possessors of cardiomyopathies familial history (diseases inducing heart muscle injuries) see a higher heart failure likelihood. Researchers undergo investigation of genetic variants hailing from varying natures, which are accountable for the heightened potentiality of heart failure (Tahhan et al., 2018). Comorbid Conditions: Diabetes, IHD, accompanied by hypertension, has undergone consistent reporting as a condition of comorbid nature, occurring within the initial heart failure hospitalization (Tahhan et al., 2018). Furthermore, individuals with diabetes see a high inclination toward heart failure, especially if individuals are also possessors of either increased blood pressure or even coronary artery disease (Tahhan et al., 2018). In addition, some instances of diabetes medications like rosiglitazone (Avandia) alongside pioglitazone (Actos) coincide with the potentiality of either worsening or inducing heart failure (Tahhan et al., 2018). Furthermore, the increase of risk pertaining to heart failure is indicative of how diabetes is accountable for inducing kidney disease. Hypertension served as the most conventional comorbid condition (Tahhan et al., 2018). Socioeconomic Status: We assessed Medicaid eligibility as a potential surrogate for socioeconomic status that might affect survival. African American patients were three times more likely to be eligible for Medicaid than were Caucasian patients. In addition, women were possessors inclining twice as high to qualify for Medicaid compared to their male counterparts (Tahhan et al., 2018). Lifestyle Factors: Immobile livelihoods, engagement in smoking, consumption of alcohol, and drug abuse can heighten heart failure. Obesity is associated with high blood pressure and type 2 diabetes, placing people at risk for heart failure. Evidence strongly suggests that obesity is a significant risk factor for heart failure, particularly in women (Tahhan et al., 2018).

Reference

Tahhan, A. S., Vaduganathan, M., Greene, S. J., Fonarow, G. C., Fiuzat, M., Jessup, M., … & Butler, J. (2018). Enrollment of older patients, women, and racial and ethnic minorities in contemporary heart failure clinical trials: a systematic review. JAMA cardiology, 3(10), 1011-1019.failure clinical trials: a systematic review. JAMA cardiology, 3(10), 1011-1019.