Question 2:Which antibiotic does the course textbook recommend for treating a UTI in breastfeeding women?
  • Answer: Short-term Fluoroquinolones
  • Rationale: This information can be found in the Summary of Key Prescribing Considerations in the chapter that covers this drug class.
Question 3:Which patients being treated with a penicillin are at high risk for toxicity? (Select all that apply)
  • Answer:
    • Renal impaired
    • Acutely ill
    • Very young
    • Very old
  • Rationale: Renal impairment causes the half-life to increase dramatically and may necessitate a reduction in dosage. In patients at high risk for toxicity (those with renal impairment, the acutely ill, the very young, and older adults), kidney function should be monitored. (p. 665)
Question 4:Which antibiotic class is most likely to be given to someone with otitis media if there are no contraindications?
  • Answer: Penicillin
  • Rationale: After 3 days of observation, start 10 days of amoxicillin or amoxicillin/clavulanate. Information found in the course module.
Question 5:Locate the Prescribers' Digital Reference website (pdr.net) to answer this question. A patient is prescribed Amoxicillin for an infection. They have a creatinine clearance of 24 mL/min. What dose of amoxicillin should they be prescribed?
  • Answer: 250-500 mg PO every 12 hours
  • Rationale: The following dosing recommendations pertain to adults. No specific dosage adjustments for pediatric patients with renal impairment are available at this time; however, dosage intervals should be adjusted. CrCl > 30 mL/min: no dosage adjustment needed. CrCl 10—30 mL/min: 250—500 mg PO every 12 hours, depending on the severity of the infection. Do not use the 875 mg-tablet strength or the extended-release tablet for dosing. CrCl < 10 mL/min: 250—500 mg PO every 24 hours, depending on the severity of the infection. Do not use the 875 mg-tablet strength or the extended-release tablet for dosing. PDR Amoxicillin
Question 6:Which medication requires patient education to avoid prolonged exposure to sunlight?
  • Answer: Tetracyclines
  • Rationale: This information can be found in the Summary of Key Prescribing Considerations in the chapter that covers this drug class.
Question 7:Using your textbook, match the antibiotic class to the patient care concern for pregnant persons. Use each option only once by selecting the option that is most true.
  • Answer: Cephalosporins - All appear to be safe for use in pregnancy.
  • Rationale: Although there are no well-controlled studies in pregnant women, evidence suggests there is no second or third trimester fetal risk.