Conclusion Six Sigma is a data-driven methodology that focuses on eliminating errors and variation in production while improving the efficiency of business processes. The approach was initially used in manufacturing companies although it can be applied in other industries including healthcare and insurance industries. Six Sigma promotes quality improvement and enhances consumer satisfaction which increases competitive advantage for businesses. Lean Six Sigma focuses on eliminating defects. In healthcare, a defect can be the difference between life and death. Use Lean Six Sigma to improve patient safety by eliminating life-threatening errors. Lean Six Sigma uses Define-Measure-Analyze-Improve-Control (DMAIC ) – a five-step approach to process improvement.